Prednisone and other corticosteroids: Balance the risks and benefits - Mayo Clinic - Serious side effects
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Prednisone is a prescribed medication that reduces swelling, irritation, and inflammation in the body for a range of conditions. While this powerful steroid drug is helpful for many, it also packs a variety of side effects, including restlessness, weight gain, and irritability. Some of the side effects can be frustrating, but remember, you are not alone.
If you need a little comic relief from the side effects of taking prednisone, check out these illustrated quotes from others who can totally relate. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.
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❿Side effects of prednisolone tablets and liquid - NHS - Prednisone and other corticosteroids
Is prednisone dangerous. Prednisone, oral tablet
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Prednisone is a prescription steroid drug. It comes as an immediate-release tablet, a delayed-release tablet, and a liquid solution.
You take all of these forms by mouth. Prednisone delayed-release tablet is available as a generic drug and as the brand-name drug Rayos. The immediate-release tablet is only available as a generic drug.
Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug. Prednisone works by weakening your immune system. If these effects are mild, they may go away within a few days or a couple of weeks. Call your doctor right away if you have serious side effects. Serious side effects and their symptoms can include the following:.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare professional who knows your medical history. Prednisone oral tablet can interact with other medications, vitaminsor herbs you may be taking.
An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help avoid interactions, your doctor should manage all of your medications carefully. Taking mifepristone with prednisone may prevent prednisone from working correctly.
Taking bupropion with prednisone may cause seizures. Taking prednisone weakens your immune system. If you receive a live vaccine while taking prednisone, your immune system might not be able to handle it properly.
This may lead to an infection. Taking prednisone with drugs that treat diabetes may result in an increase in your blood glucose levels and problems controlling your diabetes. Examples of these drugs include:. Taking warfarin with prednisone may reduce the blood-thinning effect of warfarin.
If you take these drugs together, your doctor may monitor your treatment with warfarin closely. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. Prednisone oral tablet can cause a serious allergic reaction in some people. This reaction can cause a skin rash, which can include:. Taking it again could be fatal cause death.
For people with infections: Taking prednisone weakens your immune system and can worsen an infection you already have. It also increases your risk of getting a new infection.
For people living with heart or kidney disease: Prednisone may make you retain salt and water, which can raise your blood pressure. For people living with diabetes: Prednisone can increase your blood sugar level. You might need to monitor your blood sugar level more closely. If it goes up too much, your dosage of diabetes medication might need to be changed. For people living with eye problems: Long-term prednisone use can increase your risk of getting eye infections, cataracts, or glaucoma.
Let your doctor know if you experience any vision changes or eye pain. For people living with stomach problems: Prednisone can cause damage to your stomach. Let your doctor know if you experience bad stomach pain that does not go away or you get dark or bloody stools. For people living with mood disorders: Prednisone may cause changes in your mood or behavior.
Let your doctor know if you have changes in your mood, feel depressed, or have trouble sleeping. Research in animals has shown adverse effects on the fetus when the mother takes prednisone. Studies show a risk of adverse effects to the pregnancy when the mother takes the drug. Prednisone can be passed through breast milk. For older people: As you age, your kidneys, liver, and heart may not work as well. Prednisone is processed in your liver and removed from your body through your kidneys.
It makes these organs work extra hard. For children: Children might not grow as tall if they take prednisone for several months. This dosage information is for prednisone oral tablet. All possible dosages and forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:. Dosage for children is usually based on weight. Your doctor will determine the best dosage for your child. Older adults may process drugs more slowly.
A normal adult dose may cause levels of the drug to be higher than normal. If you are aged 65 years and older, you may need a lower dose or a different dosing schedule.
For immediate-release tablets only: If you have a sudden return or worsening of your MS symptoms, you may need to take mg once per day for one week. This dosage may then be reduced to 80 mg once per day every other day for one month. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Always speak with your doctor or pharmacist about dosages that are right for you. For this drug to work well, a certain amount needs to be in your body at all times.
If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug can include:. But if your symptoms are severe, call or go to the nearest emergency room right away. What to do if you miss a dose: If you forget to take a dose, take it as soon as you remember. How to tell if the drug is working: You should experience less pain and swelling. There are also other signs that show that prednisone is effective, depending on the condition being treated.
Talk with your doctor if you have questions about whether this medication is working. Your doctor may do tests to check your health and make sure the drug is working and is safe for you. These tests may include:. Steroids such as prednisone change the amount of water and salts in your body. In large doses, prednisone can cause your body to retain salt or lose potassium.
Your doctor may recommend changes to your diet to manage this side effect. There are other drugs available to treat your condition.
Some may be better suited for you than others. Talk with your doctor about other drug options that may work for you. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date.
However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication.
The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
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Injected corticosteroids can cause temporary side effects near the site of the injection, including skin thinning, loss of color in the skin, and intense pain —. For people with infections: Taking prednisone weakens your immune system and can worsen an infection you already have. It also increases your risk of getting a. Serious side effects associated with higher doses and long-term use (greater than 1 month) are impaired wound healing, decreased growth (in. Indigestion. Take. Prednisone isn't safe to take while pregnant. You should immediately let your doctor know if you become pregnant while taking prednisone. They'll be able to explain the benefits and risks of giving your child prednisolone. I cut down to 5 mg a day. Corticosteroids are administered in many different ways, depending on the condition being treated:.Corticosteroid drugs — including cortisone, hydrocortisone and prednisone — are useful in treating many conditions, such as rashes, inflammatory bowel disease and asthma. But these drugs also carry a risk of various side effects. When prescribed in doses that exceed your body's usual levels, corticosteroids suppress inflammation. This can reduce the signs and symptoms of inflammatory conditions, such as arthritis, asthma or skin rashes. Corticosteroids also suppress your immune system, which can help control conditions in which your immune system mistakenly attacks its own tissues.
Corticosteroid drugs are used to treat rheumatoid arthritis, inflammatory bowel disease IBD , asthma, allergies and many other conditions. These drugs also help suppress the immune system in order to prevent organ rejection in transplant recipients. Corticosteroids also treat Addison's disease, a relatively rare condition where the adrenal glands aren't able to produce even the minimum amount of corticosteroid that the body needs.
Corticosteroids are administered in many different ways, depending on the condition being treated:. Corticosteroids carry a risk of side effects, some of which can cause serious health problems. When you know what side effects are possible, you can take steps to control their impact. Because oral corticosteroids affect your entire body instead of just a particular area, this route of administration is the most likely to cause significant side effects.
Side effects depend on the dose of medication you receive and may include:. When using an inhaled corticosteroid, some of the drug may deposit in your mouth and throat instead of making it to your lungs. This can cause:. If you gargle and rinse your mouth with water — don't swallow — after each puff on your corticosteroid inhaler, you may be able to avoid mouth and throat irritation.
Some researchers have speculated that inhaled corticosteroid drugs may slow growth rates in children who use them for asthma. Injected corticosteroids can cause temporary side effects near the site of the injection, including skin thinning, loss of color in the skin, and intense pain — also known as post-injection flare. Other signs and symptoms may include facial flushing, insomnia and high blood sugar. Doctors usually limit corticosteroid injections to three or four a year, depending on each patient's situation.
Corticosteroids may cause a range of side effects. But they may also relieve the inflammation, pain and discomfort of many different diseases and conditions. Talk with your doctor to help you better understand the risks and benefits of corticosteroids and make informed choices about your health. There is a problem with information submitted for this request. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID, plus expertise on managing health.
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Show references Ritter JM, et al. The pituitary and the adrenal cortex. Elsevier; Accessed Oct. Grennan D, et al. Steroid side effects.
Saag KG, et al. Major side effects of systemic glucocorticoids. Major side effects of inhaled glucocorticoids. Roberts WN, et al. Joint aspiration or injection in adults: Complications. Nieman LK. Pharmacologic use of glucocorticoids. Long-term glucocorticoid therapy. Mayo Clinic; Wilkinson JM expert opinion. Mayo Clinic.
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